Crit Care Resusc
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Randomized Controlled Trial Comparative Study
Haemodynamic effects of cold versus warm fluid bolus in healthy volunteers: a randomised crossover trial.
To test the hypothesis that changes in cardiac index and mean arterial pressure (MAP) during and after a fluid bolus (FB) are altered by fluid temperature. ⋯ Intravenous FB at body temperature leads to a greater increase in cardiac index compared with room temperature, while the reverse applies to MAP. These findings imply that in healthy volunteers, when a room temperature FB is given, the temperature of the fluid rather than its volume accounts for most of the MAP increase.