Crit Care Resusc
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Observational Study
Faecal diversion system usage in an adult intensive care unit.
To determine the frequency, indications and complications associated with the use of faecal diversion systems (rectal tubes) in critically ill patients. ⋯ Rectal tubes appear to be frequently inserted and can lead to major adverse events in critically ill patients.
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Randomized Controlled Trial
Study protocol and statistical analysis plan for the Liberal Glucose Control in Critically Ill Patients with Pre-existing Type 2 Diabetes (LUCID) trial.
Contemporary glucose management of intensive care unit (ICU) patients with type 2 diabetes is based on trial data derived predominantly from patients without type 2 diabetes. This is despite the recognition that patients with type 2 diabetes may be relatively more tolerant of hyperglycaemia and more susceptible to hypoglycaemia. It is uncertain whether glucose targets should be more liberal in patients with type 2 diabetes. ⋯ The study protocol and statistical analysis plan described will delineate conduct and analysis of the trial, such that analytical and reporting bias are minimised.
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To determine the temporal trends of incidence and outcome based on different sources of sepsis using a nationwide administrative database. ⋯ The temporal trends of sepsis incidence and mortality varied among different sources of sepsis, with lower respiratory tract being the highest burden among patients with sepsis. Furthermore, sources of sepsis and the presence of co-infection are independent predictors of mortality. Our results support source-specific preventive and treatment strategies for future sepsis management.