Arch Neurol Chicago
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Arch Neurol Chicago · Apr 2005
Randomized Controlled Trial Comparative Study Clinical TrialPallidal vs subthalamic nucleus deep brain stimulation in Parkinson disease.
Deep brain stimulation (DBS) of the globus pallidus interna (GPi) and subthalamic nucleus (STN) has been reported to relieve motor symptoms and levodopa-induced dyskinesia in patients with advanced Parkinson disease (PD). Although it has been suggested that stimulation of the STN may be superior to stimulation of the GPi, comparative trials are limited. ⋯ Stimulation of either the GPi or STN improves many features of advanced PD. It is premature to exclude GPi as an appropriate target for DBS in patients with advanced disease.