J Rheumatol
-
Randomized Controlled Trial
Efficacy and tolerability of celecoxib in the treatment of acute gouty arthritis: a randomized controlled trial.
To evaluate the analgesic efficacy of high-dose celecoxib in the treatment of moderate to extreme pain and inflammation associated with acute gouty arthritis. ⋯ High-dose celecoxib (800/400 mg) was significantly more effective than low-dose celecoxib (50 mg bid) and comparable to indomethacin in the treatment of moderate to extreme pain in patients with acute gouty arthritis. Further, celecoxib was well tolerated.