Hepatob Pancreat Dis
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Hepatob Pancreat Dis · Feb 2015
Review Meta AnalysisContinuous regional arterial infusion for the treatment of severe acute pancreatitis: a meta-analysis.
Continuous regional arterial infusion (CRAI) is a drug delivery system, which dramatically increases the drug concentration in the pancreas. Previous clinical and basic studies have demonstrated the possible therapeutic efficacy of CRAI for severe acute pancreatitis (SAP). This meta-analysis of all published randomized controlled trials (RCTs) was conducted to assess the efficacy and safety of CRAI for the treatment of SAP. ⋯ CRAI is effective for the treatment of SAP, and the combination of drug administration via CRAI did not have a significant effect on the improvement of the outcomes.