Acta Physiol Hung
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Sepsis-associated encephalopathy is a multifactorially determined process of the brain parenchyma. Among other factors, vasogenic causes have been shown to play a role in its development. The aim of the present work was to assess whether cerebral tissue oxygen saturation is influenced by administration of acetazolamide in septic patients compared to controls. ⋯ Cerebral vasoreactivity to acetazolamide is preserved in patients with severe sepsis.