The Medical journal of Australia
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Six patients with aplastic anaemia, and nine patients with acute leukaemia in relapse, underwent bone-marrow transplantation between November, 1975, and November, 1979. All patients with aplastic anaemia developed a functioning marrow graft and four were alive 42, 24, 22, and 17 months respectively after the procedure. ⋯ However, two patients remained alive, with no evidence of recurrent leukaemia, 18 and nine months respectively after the graft. These results confirm that bone-marrow transplantation is a useful therapeutic procedure in severe aplastic anaemia, but is of limited value in the treatment of acute leukaemia in relapse.
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Historical Article
Centenary oration. Evolution of responsibilities in the care of health.
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Low back pain, referred pain in the lower limbs, and spasm of the back, gluteal, and hamstring muscles are clinical features which can be induced in normal volunteers by stimulating structures which are innervated by the lumbar dorsal rami. Conversely, they can be relieved in certain patients by selective interruption of conduction along dorsal rami. ⋯ The pathophysiology, pathology, and treatment of this syndrome are described. Recognition of this syndrome, and its treatment with relatively minor procedures, can obviate the need for major surgery which might otherwise be undertaken.