Ann Acad Med Singap
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Ann Acad Med Singap · Jun 2021
Multicenter Study Observational StudyPredictors and outcomes of high-flow nasal cannula failure following extubation: A multicentre observational study.
Despite adhering to criteria for extubation, up to 20% of intensive care patients require re-intubation, even with use of post-extubation high-flow nasal cannula (HFNC). This study aims to identify independent predictors and outcomes of extubation failure in patients who failed post-extubation HFNC. ⋯ Post-extubation HFNC failure, especially in patients with stroke as a comorbidity, remains a clinical challenge and predicts poorer clinical outcomes. Our observational study highlights the need for future prospective trials to better identify patients at high risk of post-extubation HFNC failure.