Ann Acad Med Singap
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Ann Acad Med Singap · Aug 2022
Interaction of sex and diabetes in Asian patients with heart failure with mildly reduced left ventricular ejection fraction.
The impact of sex and diabetes mellitus (DM) on patients with heart failure with mildly reduced ejection fraction (HFmrEF) is not well elucidated. This study aims to evaluate sex differences in the clinical profile and outcomes in Asian HFmrEF patients with and without DM. ⋯ Asian women with HFmrEF had a higher prevalence of DM, with differences in clinical characteristics, compared to men. While diabetes conferred poor outcomes regardless of sex, there were distinct sex differences. These highlight the need for sex-specific management strategies.