Ann Acad Med Singap
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Ann Acad Med Singap · Jun 2023
Comparative StudyComparison of existing methods of low-density lipoprotein cholesterol estimation in patients with type 2 diabetes mellitus.
Elevated low-density lipoprotein cholesterol (LDL-C) is an important risk factor for atherosclerotic cardiovascular disease (ASCVD). Direct LDL-C measurement is not widely performed. LDL-C is routinely calculated using the Friedewald equation (FLDL), which is inaccurate at high triglyceride (TG) or low LDL-C levels. We aimed to compare this routine method with other estimation methods in patients with type 2 diabetes mellitus (T2DM), who typically have elevated TG levels and ASCVD risk. ⋯ We demonstrated strong correlations between newer methods of LDL-C estimation, FLDL, and DLDL. At higher TG concentrations, no equation performed well. The Martin/Hopkins equation had the least discordance with DLDL, and may minimise misclassification compared with the FLDL and SLDL.
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Ann Acad Med Singap · Jun 2023
Editorial LetterA perfect match: The story of robotics in gynaecology.