Arch Iran Med
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Monosomy 18p syndrome is one of the prototypical examples of autosomal terminal deletions. This deletion can be the consequence of de novo deletions, malsegregation of a balanced parental translocation, cryptic subtelomeric deletions or ring chromosome 18. The present case is a rare cytogenetic variant of monosomy 18 as a consequence of whole-arm translocation between chromosomes 13 and 18 which has been reported only three times previously.
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Migraine is a debilitating neurological disorder with a high prevalence. This study was conducted to evaluate the relationship between body mass index (BMI) and disability, severity, frequency and duration of headaches in female migraine patients. ⋯ This study revealed that migraineurs with higher BMI experienced higher headache frequency, severity and duration as well as higher disability score.
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The aim of this study was to assess the current applicability of articles that show important advances in medicine. The recruited papers include those published fifty years ago in the most respected journals in the USA, England and Germany. Using PubMed Central citations since 2010, original articles closely related to papers published in 1966 in the New England Journal of Medicine (NEJM), the Lancet and the Deutsche Medizinische Wochenschrift (DMW) were identified. ⋯ The number of highly relevant articles still currently cited were determined as 12/298 (4%) in the NEJM, 11/ 628 (1.7%) in the Lancet and 1/221 (0.45%) in the DMW (0.45%). It was concluded that "halfhundred years impact index" should be regarded as a measure of 'relevance and quality over time'. Combined with impact factor, it could be a better indicator for importance of scientific journals.