Bratisl Med J
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Randomized Controlled Trial Comparative Study
The comparison of the effects of T-piece and CPAP on hemodynamic parameters, arterial blood gases and success of weaning.
Weaning from mechanically ventilation is a period of transition from total ventilatory support to spontaneous breathing. The aim of this study was to compare the effects of T-Piece and continuous positive airway pressure (CPAP) on hemodynamic parameters, arterial blood gases and success of weaning. In a prospective, randomized, controlled trial, 40 consecutive patients requiring mechanically ventilation in our 8-bed adult general intensive care unit (ICU) for >48 hrs were considered eligible for this study. ⋯ There were no significant differences within and between T-piece and CPAP groups according to hemodynamic parameters and arterial blood gases at the weaning period. The number of patients who could be unsuccessful weaned in the T-piece group was higher than the number of patients in the group CPAP (p < 0.001, p < 0.01). Whether, the technique used to wean patients, in this setting, resulted in a clinically relevant improvement in the outcomes addressed above requires further carefully designed, randomized, controlled trials (Tab. 4, Ref. 25).
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Primary or secondary orbital melanomas are extremely rare tumors; they represent less than 1% of primary orbital neoplasms. Over 90% of primary orbital melanomas arise from melanocytes (congenital ocular melanosis, oculodermal melanosis). ⋯ C69) were treated with radical surgery, combined techniques or isolated stereotactic radiosurgery, 45 (57%) patients with ciliary body and choroidal melanomas were treated with primary enucleation, 34 (43%) patients were managed with combined techniques (parsplana vitrectomy with endoresection, brachytherapy plus stereotactic radiosurgery) or with "conservative treatment", namely with stereotactic radiosurgery alone. In group of melanoma patients, primary orbital melanoma was present only in 1 case (1 %) (Fig. 4, Ref. 5).