Bratisl Med J
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Randomized Controlled Trial
Caesarean section in isobaric spinal anesthesia with and without direct preoperative hydration with crystalloids.
Because the direct preoperative hydration with crystalloids (20 ml/kg) does not adequately prevent spinal hypotension during cesarean section, the authors investigated whether a continuous intravenous infusion of ephedrine (50 mg/500 ml of Ringer solution) without preoperative hydration would prevent the spinal hypotension more effectively. ⋯ The continuous infusion of ephedrine simultaneously with spinal anesthesia is superior to direct preoperative hydration with crystalloids in preventing the spinal hypotension and its clinical manifestations in parturients delivered with C-section (Tab. 3, Ref. 20).
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Randomized Controlled Trial
Comparison of alfentanil and remifentanil infusions in combination with propofol for the outpatient extra-corporeal shock wave lithotripsy.
The aim of this study is to compare the efficiency of propofol+remifentanil to propofol+alfentanil in reducing pain in patients with urinary system stones undergoing outpatient Extracorporeal Shock Wave Lithotripsy (ESWL). ⋯ We concluded that both methods may be successfully used for patients undergoing ESWL (Tab. 6, Rief. 29).
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Randomized Controlled Trial Comparative Study
Postoperative intrathecal analgesia for primary total hip arthroplasty--comparative clinical examination of two different small doses of morphium hydrochloride.
To prospectively compare the spinal analgesia with two different small doses of morphium hydrochloride after primary total hip arthroplasty. ⋯ Intrathecal usage of 0.05 mg and 0.1 mg of MCh provides a long-lasting postoperative analgesia. It is a practical method to be provided after primary total hip arthroplasty. The efficacy of 0.1 mg of MCh is greater compared to that of 0.05 mg of MCh. These doses of MCh do not cause respiratory depression but cause nausea, vomiting and itching (Tab. 4, Fig. 1, Ref. 11).
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Randomized Controlled Trial
Prevention of postoperative nausea and vomiting with a small dose of propofol combined with dexamethasone 4 mg or dexamethasone 8 mg in patients undergoing middle ear surgery: a prospective, randomized, double-blind study.
Postoperative nausea and vomiting (PONV) is a common complication after middle ear surgery. We have aimed to compare the administration of a subhypnotic dose of propofol with dexamethasone 4 mg or 8 mg and placebo in prevention of postoperative nausea and vomiting (PONV) after middle ear surgery. ⋯ The administration of a subhypnotic dose of propofol plus 4 mg of dexamethasone at the end of surgery was found to be at least as effective as propofol plus 8 mg of dexamethasone in preventing the PONV in the early postoperative period in adult patients undergoing middle ear surgery (Tab. 4, Ref. 34).
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Randomized Controlled Trial Comparative Study
The comparison of the effects of T-piece and CPAP on hemodynamic parameters, arterial blood gases and success of weaning.
Weaning from mechanically ventilation is a period of transition from total ventilatory support to spontaneous breathing. The aim of this study was to compare the effects of T-Piece and continuous positive airway pressure (CPAP) on hemodynamic parameters, arterial blood gases and success of weaning. In a prospective, randomized, controlled trial, 40 consecutive patients requiring mechanically ventilation in our 8-bed adult general intensive care unit (ICU) for >48 hrs were considered eligible for this study. ⋯ There were no significant differences within and between T-piece and CPAP groups according to hemodynamic parameters and arterial blood gases at the weaning period. The number of patients who could be unsuccessful weaned in the T-piece group was higher than the number of patients in the group CPAP (p < 0.001, p < 0.01). Whether, the technique used to wean patients, in this setting, resulted in a clinically relevant improvement in the outcomes addressed above requires further carefully designed, randomized, controlled trials (Tab. 4, Ref. 25).