Bratisl Med J
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Randomized Controlled Trial Comparative Study
Comparison of antibacterial effects of oral rinses chlorhexidine and herbal mouth wash in patients admitted to intensive care unit.
Mouthwashes decrease the risk of VAP by reducing the number of microorganisms and their transmission and colonization in the lung. Among the oral rinses, chlorhexidine is considered as the gold standard but it has a variety of complications. The purpose of this study was to determine and compare anti-bacterial effects of the chlorhexidine gluconate and herbal mouthwashes in intensive care unit patients. ⋯ The herbal mouth wash has significant antibacterial effects against Staphylococcus aureus and Streptococcus pneumoniae, but its efficacy is less than chlorhexidine, so after further investigation, it would be considered as an alternative to chlorhexidine in ICUs (Tab. 3, Ref. 33).
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Randomized Controlled Trial
Adding magnesium to levobupivacaine for axillary brachial plexus block in arteriovenous fistule surgery.
The aim of this study was to compare the effect of adding magnesium to levobupivacaine on sensory and motor block onset and duration for axillary brachial plexus block in chronic renal failure (CRF) patients scheduled for arteriovenous fistule surgery (AVFS). ⋯ We conclude that by its decreasing effect on local anesthetic dose, magnesium may reduce the side effects due to high local anesthetic doses in patients with CRF (Tab. 1, Ref. 11).
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This study was conducted to determine the association of insertion/deletion (I/D) polymorphism of the ACE gene in hypertensive and T2DM subjects in Egyptian population. ⋯ The DD genotype and the D allele are associated with hypertension and type 2 diabetes in Egyptian patients (Tab. 5, Fig. 1, Ref. 32).
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Vasculitis in childhood is a result of a spectrum of causes ranging from idiopathic conditions with primary vessel inflammation to syndromes after exposure to recognized antigenic triggers, such as infectious agents and drugs causing hypersensitivity reactions. Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. Although there is often a history of a recent or simultaneous upper respiratory tract infection, no consistent causative organism is found. We report an 11-year old boy with HSP and brucellosis and we speculated that brucellosis was the trigger agent for HSP (Ref. 13). ⋯ brucellosis, trigger agent, Henoch-Schönlein purpura, vasculitis, infectious agents, drug, hypersensitivity reactions, primary vessel inflammation.
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In this study, we investigated the protective effects of frequently used intravenous anesthetics (ketamine, propofol, thiopental, and fentanyl) in oxidative stress in a rat liver model of obstructive jaundice. ⋯ Ketamine and propofol were observed to cause the least amount of oxidative stress in this rat model of induced oxidative stress generated by ligation of the common bile duct. This experiment is the first study on this subject in the literature (Tab. 3, Ref. 65).