Bratisl Med J
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Type 2 Diabetes Mellitus (DM2) can lead to autonomic nervous system dysfunction and heart rate variability (HRV) is often used to assess this system both during rest and during physical exercise. ⋯ There was no difference between the groups in the modulation of rest or in the parasympathetic adjustments of the exercise (Tab. 4, Ref. 32).
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The objective of the research is to determine the levels of vitamin D and trace elements in the umbilical cord blood, as well as to evaluate the clinical and laboratory characteristics in premature newborns with congenital pneumonia. ⋯ Our results demonstrated a high prevalence of 25 (OH) vitamin D deficiency in premature newborns. A significant relationship has been shown between the respiratory status of vitamin D and presence of congenital pneumonia in premature newborns. The analysis also showed that the content of trace elements in premature newborns plays an immunomodulatory role and affects the susceptibility and outcome of the infectious process. Thrombocytopenia in premature newborns may be an early biomarker for monitoring congenital pneumonia (Tab. 2, Ref. 28). Text in PDF www.elis.sk Keywords: congenital pneumonia, premature newborn, vitamin D, trace elements, mass spectrometry.
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Purpose of this study was to evaluate properties of apelin, a peptide detectable in peripheral blood, for atrial fibrillation (AF) detection in a diverse population of patients covering a broad spectrum from healthy to polymorbid patients. ⋯ Apelin might be a promising biomarker for detecting AF in our study population. These results suggest promising potential of apelin as a screening biomarker for AF (Tab. 2, Fig. 1, Ref. 46). Text in PDF www.elis.sk Keywords: biomarker, apelin, arrhythmia, atrial fibrillation.
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The pregnancy is accepted as an independent risk factor for restless legs syndrome/Willis-Ekbom disease (RLS/WED). The neutrophil-to-lymphocyte ratio (NLR) was recently reported in the pathophysiology of RLS/WED. In this report, we investigated the relationship between the presence of RLS/WED and the levels of NLR in pregnancy. ⋯ These results may suggest that an increased inflammation demonstrated by the increased NLR, may, in part, play a role in higher prevalence of RLS/WED in pregnancy, especially in late gestational weeks (Tab. 2, Fig. 1, Ref. 34). Text in PDF www.elis.sk Keywords: neutrophil-to-lymphocyte ratio, restless legs syndrome/Willis-Ekbom disease, pregnancy, inflammation.
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Multicenter Study
Risk of genitourinary malignancy in patients that receive anticoagulant or antiplatelet therapy.
Haematuria is a common indication for a urology evaluation. In many cases, its cause is not determined unequivocally, but it does not pose any threat to the patient. However, it can represent the first symptom of urinary tract cancer. ⋯ Malignancy risk for patients who received anticoagulant or antiplatelet therapy was similar to the risk observed in the general population. Antiplatelet and anticoagulant therapy were not significant risk factors of urological malignancy in patients with haematuria. The results from the present study will be used in a power analysis for an upcoming multicentre study (Tab. 4, Ref. 17). Text in PDF www.elis.sk Keywords: anticoagulation therapy, antiplatelet therapy, cancer, haematuria, risk factor.