Bratisl Med J
-
Diabetic Retinopathy (DR) is a widespread intense stage of diabetes mellitus that causes vision-effecting anomalies in the retina. It is a medical health condition on the strength of fluctuating glucose level in the blood that can result in vision loss in case of severity. ⋯ In the current research, an innovative HHO-CBL was developed for identifying the primary causes that lead to the formation of microaneurysms and diagnosing all five grades of DR. According to the acquired results presented through the evaluation performance metrics indicates that the pre-early diagnosis and five grade classification using feature embedding technique outperformed the other prevailing approaches (Tab. 4, Fig. 10, Ref. 31).
-
Clinical swabs with suspected viral infection are usually transported in virus transport medium (VMT). During epidemics/pandemics, tampons without VTM would be more suitable for saving space and cost. This study was conducted to verify the applicability of throat swabs without VTM in the diagnosis/screening of enteroviral infections by polymerase chain reaction (PCR) in a volunteer study group. ⋯ When processed immediately, the results for all three swab types were compatible. Swabs without VTM may be used for collection of clinical samples in the diagnosis of suspected enteroviral infections or as potential screening tools for enteroviruses (Tab. 2, Ref. 15). Keywords: enterovirus infection, swab, transport medium, PCR, molecular diagnostics.
-
Prostate cancer is a significant health issue worldwide, with varying incidence and mortality rates across different regions. This study focuses on Slovakia, a country with an increasing trend in number of prostate cancer cases. The manuscript aims to provide a comprehensive overview of the burden of prostate cancer in Slovakia, encompassing epidemiological trends, economic impact, diagnostic approaches, and treatment modalities. The study emphasizes the need for effective management strategies and healthcare policies to address the increasing burden of this disease in the Slovak population. ⋯ The burden of prostate cancer in Slovakia is significant and growing, with rising incidence and economic costs posing challenges to the healthcare system. The study underscores the need for improved and early access to effective diagnostic and treatment options, and robust health policies to manage the rising burden. Additionally, public health initiatives focusing on awareness and early detection could play a crucial role in reducing the impact of prostate cancer in Slovakia. The findings of this study contribute valuable insights for policymakers and healthcare providers in developing targeted strategies to mitigate the burden of prostate cancer in the Slovak population (Tab. 7, Ref. 53).
-
The aim of this study is to determine the role of Respiratory Rate Oxygenation (ROX), shock, and diastolic shock indexes in predicting mortality in coronavirus disease 2019 (COVID-19) patients admitted to the emergency department. ⋯ In conclusion, we found that the ROX index had higher sensitivity and specificity than other indexes in predicting mortality in the evaluation of COVID-19 patients (Tab. 3, Fig. 2, Ref. 18).
-
The goal of our work was to develop a composition for antimicrobial photodynamic inactivation (aPDI) of anaerobic periodontopathogenic pathogens. ⋯ aPDT is a promising therapeutic alternative for the local treatment of purulent-inflammatory diseases of various localisation caused by antibiotic-resistant bacteria, including in the oral cavity (Fig. 3, Ref. 57). Text in PDF www.elis.sk Keywords: peri-implant diseases, photodynamic therapy, photosensitiser, anaerobic bacteria.