Chinese Med J Peking
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Chinese Med J Peking · Oct 2010
Randomized Controlled TrialPulmonary artery perfusion with HTK solution prevents lung injury in infants after cardiopulmonary bypass.
Pulmonary artery perfusion during cardiopulmonary bypass (CPB) is a novel adjunctive method, which can minimize the lung ischemic-reperfusion injury and inflammatory response. This study evaluated the protective effect of pulmonary perfusion with hypothermic HTK solution in corrections of congenital heart defects with pulmonary hypertension. ⋯ In infants with congenital heart defects, pulmonary perfusion with hypothermic HTK solution during cardiopulmonary bypass could ameliorate lung function and reduce the inflammatory response.