Chinese Med J Peking
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Chinese Med J Peking · Aug 2011
Review Case ReportsDocetaxel-induced nail toxicity: a case of severe onycholysis and topic review.
Docetaxel is a commonly-used anti-cancer chemotherapeutic agent given its efficacy in a large variety of solid tumors. It is associated with various adverse effects one of which is nail toxicity. We report a case of severe onycholysis as a result of treatment with docetaxel in a patient who suffered from metastatic nasopharyngeal carcinoma. The case report will be followed by a discussion on the possible mechanism and preventive strategies for taxane-induced nail toxicity.