Chinese Med J Peking
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Chinese Med J Peking · Apr 2012
Multicenter Study Comparative Study Clinical TrialEvaluation of entropy for monitoring the depth of anesthesia compared with bispectral index: a multicenter clinical trial.
As a new electroencephalogram (EEG) signal processing technique for monitoring the depth of anesthesia, entropy consists of two indices: reaction entropy (RE) and state entropy (SE). Our study compared entropy with classical bispectral index (BIS) in reduction of myoelectrical interference and noxious stimuli with EEG signals. ⋯ This large-sample multicentric study confirmed the values of RE and SE as approximating BIS value, at the onset of unconsciousness during propofol TCI anesthesia. After elimination of myoelectrical activation, all values of RE, SE and BIS decreased significantly and the three indices were less sensitive to noxious stimuli than cardiovascular responses.