Clin Med
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Non-invasive ventilation (NIV) has become the standard of care for most patients with ventilatory failure due to an acute exacerbation of chronic obstructive pulmonary disease (COPD). In all but a small minority, even of the very sickest, there is little to be lost by at least a short trial of NIV. ⋯ There are no randomised controlled trials of NIV in patients with acute ventilatory failure due to obesity but the outcome from invasive ventilation is poor and the results of NIV encouraging. Finally, NIV may have a role during the transition from active care, aimed to extend life, to palliative care.
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The incidence of idiopathic normal pressure hydrocephalus (INPH) is seen to be relatively rare, ie about two per million inhabitants per year. Five studies on the prevalence of INPH in elderly patients, from three countries, have been published between 1985 and 2009.1-5 Prevalence ranged from 0.41% to 2.94% (mean 0.8%), ie slightly less than one per 100 based on samples ranging from 170 to 982 subjects. ⋯ Attempts to identify all patients with INPH overlook many cases. INPH is actually a very common disease and its prevalence increases with age.