Cochrane Db Syst Rev
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Cochrane Db Syst Rev · Jul 2007
Retracted PublicationWITHDRAWN: Effect of antihypertensive drugs on mortality, morbidity and blood pressure in blacks.
Black people have a greater prevalence of elevated blood pressure leading to excess morbidity and mortality. ⋯ When first-line drugs from different classes are compared in the treatment of black people, there is no evidence of differential effects on most mortality and morbidity outcomes. Those morbidity differences that were found favoured diuretics. Drugs differ in their ability to reduce blood pressure in black people. Calcium blockers were the only drug class that reduced blood pressure in all subgroups of black people including those with severe hypertension. Beta-blockers, angiotensin receptor blocker, alpha blockers and ACE Inhibitors were least good at reducing blood pressure in black adults.