Cochrane Db Syst Rev
-
Cochrane Db Syst Rev · Aug 2010
Review Meta AnalysisAlternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia.
Magnesium sulphate remains the drug of choice for both prevention and treatment of women with eclampsia. Regimens for administration of this drug have evolved over the years, but have not yet been formally evaluated. ⋯ Although strong evidence supports the use of magnesium sulphate for prevention and treatment of eclampsia, trials comparing alternative treatment regimens are too small for reliable conclusions.
-
Cochrane Db Syst Rev · Aug 2010
Review Meta AnalysisAlternative magnesium sulphate regimens for women with pre-eclampsia and eclampsia.
Magnesium sulphate remains the drug of choice for both prevention and treatment of women with eclampsia. Regimens for administration of this drug have evolved over the years, but have not yet been formally evaluated. ⋯ Although strong evidence supports the use of magnesium sulphate for prevention and treatment of eclampsia, trials comparing alternative treatment regimens are too small for reliable conclusions.
-
Cochrane Db Syst Rev · Aug 2010
Review Meta AnalysisVaccines for preventing cholera: killed whole cell or other subunit vaccines (injected).
Injected cholera vaccines are rarely used today, although they may have some benefit. It is valuable to summarize the evidence for effectiveness of injected cholera vaccines for comparison with newer oral vaccines (subject of a separate Cochrane Review). ⋯ Injected cholera vaccines appear to be safe and relatively more effective than usually realized. Protection against cholera persists for up to two years following a single dose of vaccine, and for three years with an annual booster. However, they have been superseded by oral vaccines.
-
Cochrane Db Syst Rev · Aug 2010
Review Meta AnalysisVaccines for preventing cholera: killed whole cell or other subunit vaccines (injected).
Injected cholera vaccines are rarely used today, although they may have some benefit. It is valuable to summarize the evidence for effectiveness of injected cholera vaccines for comparison with newer oral vaccines (subject of a separate Cochrane Review). ⋯ Injected cholera vaccines appear to be safe and relatively more effective than usually realized. Protection against cholera persists for up to two years following a single dose of vaccine, and for three years with an annual booster. However, they have been superseded by oral vaccines.
-
Cochrane Db Syst Rev · Aug 2010
Review Meta AnalysisFetal and umbilical Doppler ultrasound in normal pregnancy.
One of the main aims of routine antenatal care is to identify the 'at risk' fetus in order to apply clinical interventions which could result in reduced perinatal morbidity and mortality. Doppler ultrasound study of umbilical artery waveforms helps to identify the compromised fetus in 'high-risk' pregnancies and, therefore, deserves assessment as a screening test in 'low-risk' pregnancies. ⋯ Existing evidence does not provide conclusive evidence that the use of routine umbilical artery Doppler ultrasound, or combination of umbilical and uterine artery Doppler ultrasound in low-risk or unselected populations benefits either mother or baby. Future studies should be designed to address small changes in perinatal outcome, and should focus on potentially preventable deaths.