J Formos Med Assoc
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Controlled Clinical Trial
Pharmacokinetics of vancomycin in adults receiving extracorporeal membrane oxygenation.
Extracorporeal membrane oxygenation (ECMO) alters the pharmacokinetics (PK) of vancomycin in neonates; but data on adults is limited. ⋯ Vancomycin clearance in patients receiving ECMO with a roller pump was significantly lower than that in the matched cohort. Vancomycin PK parameters in patients on ECMO with a centrifugal pump were comparable to those in the matched control group.