Med Klin
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Multicenter Study Clinical Trial
[Molecular biology studies of a multicenter phase III study (SIC Study)].
Transcription factors adjust the up- and downregulation of inflammatory genes. Within the bounds of the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S. ⋯ S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecular biological level.