Pak J Med Sci
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Catalase (CAT) is an important endogenous antioxidant enzyme that detoxifies H2O2 into water and oxygen, consequently limiting the deleterious effects of reactive oxygen species. It has suggested that CAT-21A/T (rs7943316) OMIM: 115500 gene promoter polymorphism is predominantly associated with different human disorders such as hypertension, cancers, diabetes, nephropathy, and other diseases accompanied by oxidative stress. This study was designed to investigate the prevalence of mutant T allele frequency in healthy individuals. ⋯ Data demonstrates that frequency and distribution of mutant T allele was more prevalent as compared to wild type A allele in the study group.
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To compare the effects of Pars Plana Vitrectomy (PPV) and Scleral Buckling (SB) with reference to Central Corneal Thickness (CCT), Corneal Endothelial-Cell Density (CED), Anterior Chamber Depth (ACD) and Axial Length (AL) in repair of Rhegmatogenous Retinal Detachment (RRD). ⋯ Rhegmatogenous retinal detachment repair causes ocular changes, with significantly more decrease in corneal endothelial cell density after pars plana vitrectomy, and more increase in anterior chamber depth and axial length after scleral buckling.
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To determine clinical outcome in patients with cervical injury after lateral mass screws fixation in a tertiary care hospital. ⋯ Lateral mass screws technique is a safe and effective method for cervical fixation after proper reduction.
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To determine the effectiveness of Test-Enhanced learning as a learning tool in lectures for undergraduate medical students. ⋯ Test-enhanced learning has significant effect on improving the learning of course content delivered to undergraduate medical students through lectures.
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To explore the correlation of dual-source computed tomography (DSCT)/dual-energy imaging with pathological grading of lung adenocarcinoma. ⋯ HD and LD groups could be predictably distinguished by single-energy images at low energy levels (40-70 keV) in the venous phase. Quantitative analysis of NIC in the venous phase is also valuable for predicting the pathological grade of lung adenocarcinoma.