Pak J Med Sci
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The objective of the study was to assess the efficacy and safety profile of 2nd line Anti TB drugs in DR TB patients in a tertiary care hospital of South Punjab. ⋯ The study findings suggest the efficacy of second-line anti-TB drug regimens in achieving sputum smear conversion and positive treatment outcomes in patients with MDR-TB. However, the occurrence of ADRs highlights the need for careful monitoring and management during treatment.
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Burden of congenital and hereditary anomalies in the population of Azad Jammu and Kashmir, Pakistan.
This study was aimed to elucidate the prevalence-pattern of congenital and hereditary anomalies (CA) in the population of Azad Jammu and Kashmir (AJK), which is a logistically difficult area in the north-east of Pakistan and in the foot-hills of Himalayas. ⋯ Majority of the anomalies observed in this cohort are of severe nature rendering high morbidity burden on the population and require early detection, intervention and management.
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To examine the expression of circular ribonucleic acid (circRNA) in the peripheral blood of pregnant women with preeclampsia (PE) prior to the onset of the disease. ⋯ CircRNAs are involved in a variety of biological processes and regulatory network related to the pathogenesis of PE.
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To determine the association of serum Vitamin-D levels and placental laminin expression in pre-eclamptic and normotensive women. ⋯ Our results show a strongly positive association between serum Vitamin-D levels, LN expression and severity of histopathological changes between normotensive and pre-eclamptic women.
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Medical and health care traverse geographical boundaries in the form of "Medical Tourism" with patients travelling from low and middle-income countries to developed nations and vice versa as well. Affordable medical care is also attracting patients from developed nations to countries like India, Thailand, UAE and others with international accreditation playing a key role. This also yields economic benefits for the recipient countries. ⋯ For this, literature search was conducted using google, Bing, google scholar, PubMed, web of science to search engines and data bases. One hundred eighty articles, reports & publications were downloaded of which 25 non-English & duplicates, and 75 irrelevant records were excluded. Hence, 34 references of relevant English language articles, publications, reports and online resources were utilized for the review.