Pak J Med Sci
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Case Reports
Adult-onset chronic recurrent multifocal osteomyelitis: A case report of a rare entity.
Chronic recurrent multifocal osteomyelitis is a rare autoimmune disorder causing inflammatory joint lesions. It has an estimated prevalence of 1-2 per million while adult-onset disease constitutes only 6.3% of patients. ⋯ We present a case of a 44 years old male who presented to the rheumatology clinic with lower back pain for twelve years. Magnetic resonance imaging of the lumbosacral spine showed ovoid areas of abnormal signal intensities along superior and inferior endplates of multiple vertebrae of the dorsolumbar and sacral spine. Computed tomography guided biopsy of L4 vertebrae was done. Histopathology revealed linear cores of degenerating fibrocartilage focally exhibiting small spicules of mineralized bone and fibro-collagenous tissue. He initially did not respond to traditional therapy. His symptoms improved with the addition of a Janus Kinase inhibitor. To the best of our knowledge, this is the first case of chronic recurrent multifocal osteomyelitis to be reported from Pakistan.
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This study aimed to explore the perceptions of frontline Healthcare Workers (HCWs) towards managing COVID-19 in Tertiary care hospital in Pakistan. ⋯ Negative emotions predominated in the beginning and positive emotions emerged gradually. PPE and administrative support played significant role. HCWs' mental health was maintained in part by their self-coping styles. The findings of this study can be employed to inform and enhance future pandemic response initiatives.
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To compare the clinical effects of applying a 3D-printed ACT titanium trabecular intervertebral fusion cage and a Polyetheretherketone (PEEK) cage in posterior lumbar interbody fusion (PLIF). ⋯ Applying a 3D-printed ACT titanium trabecular intervertebral fusion cage or PEEK cage in PLIF has the potential to improve clinical symptoms of patients with degenerative lumbar diseases, and restore the Cobb angle and intervertebral height. 3D-printed ACT titanium trabecular intervertebral fusion cage can accelerate intervertebral fusion without increasing operation related complications.
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To synthesize contemporary evidence of the impact of contralateral prophylactic mastectomy (CPM) on survival outcomes in patients with unilateral breast cancer (UBC). ⋯ Our results provide strong evidence supporting the positive impact of CPM on survival outcomes in patients with UBC. Further research and long-term follow-up studies are warranted to validate these findings.
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This study aimed to explore the qualitative aspects of nursing undergraduates' experience of participating in the Internet + nursing program and their spiritual education needs from the perspective of the Neuman system model. ⋯ At the school and hospital level, importance should be placed on the basic education of spirituality and psychological nursing, and appropriate measures should be taken to improve the knowledge level of spirituality and psychological nursing as well as the capacity of spiritual nursing, in order to ensure high-quality nursing services.