Pak J Med Sci
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To observe any association between mental health and potential contributors, i.e., BMI, eyesight, and number of screen-based devices in young adults. ⋯ Students who used only smartphones had significantly lower MWB scores than those who used smartphones and laptops. The study found low MWB scores among underweight individuals and those who were with both eye-sight issues i.e. myopia as well as hyperopia.
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Current research aims to monitor the prevalence of Acinetobacter baumannii (A. baumannii) in healthcare facilities due to the development of resistance to antimicrobials. The study aimed to elucidate the interplay between antibiotic resistance and biofilm formation, two key factors contributing to virulence of bacteria. ⋯ This study concluded that A. baumannii isolated from the patients with urinary tract infections had resistance to routinely used antibiotics. The isolates have shown hemolysis pattern (α & γ) and tendency to make biofilms. Moreover, except for ceftriaxone which showed negative correlations, a positive correlation was observed between biofilm biomass and the resistance profile to the remaining three antibiotics.
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To investigate the clinical value of EGFR mutation testing in peripheral blood of patients with non-small cell lung cancer. ⋯ EGFR mutation in peripheral blood and tumor tissues is highly consistent in NSCLC patients. The EGFR mutation rate is higher in adenocarcinoma and non-smoking patients, and the prognosis is better in patients with EGFR mutations.
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Encephalocele is a congenital neural tube defect (NTD). The pathophysiology of the NTDs is exceedingly complex. Numerous explanations have been proposed to explain it. ⋯ Double encephalocele is a rare entity. The multisite closure theory appears to be the most plausible explanation for the development of multiple NTDs. The management of double encephalocele requires a case based approach.
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Congenital malformations (CM) are structural defects of the human body that arise during development. They significantly impact neonatal outcomes such as morbidity and mortality, hence identification of risk factors and their reduction is vital to improve materno-fetal outcomes. In Karachi, Pakistan, there is insufficient data on the incidence of congenital malformations. Therefore, it is necessary to initiate a prospective case control study. The desired objective was to determine the association of congenital malformations with sociodemographic and maternal risk factors in different ethnicities. ⋯ It was evident that various maternal sociodemographic and risk factors play a significant role in the development of congenital anomalies.