Rev Assoc Med Bras
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Randomized Controlled Trial
[The effect of oral ondansetron in the prevention of postoperative nausea and vomiting].
Not so many years ago, the incidence of postoperative nausea and vomiting used to reach 40% to 50%. More recent publications indicate that this complication still reaches considerable frequency: 20 to 30%. The present study had the objective of evaluating the impact of oral administration of ondansetron on the incidence of postoperative nausea and vomiting among patients submitted to general anesthesia. ⋯ Ondansetron, 16 mg orally, administered before the operation significantly reduced the incidence of postoperative nausea and vomiting. The simplicity of administration and low cost of this presentation justify the choice of this administration route.
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Randomized Controlled Trial Clinical Trial
[Racemic bupivacaine, levobupi vacaine and ropivacaine in regional anesthesia for ophthalmology -- a comparative study].
Racemic bupivacaine, used in peribulbar anesthesia owing to its high potential to promote motor blockade, presents a smaller safety margin for cardiotoxicity in relation to ropivacaine and levobupivacaine. The objective of this study was to compare the degree of motor blockade and alteration of intraocular pressure (IOP) produced by racemic bupivacaine, levobupivacaine and ropivacaine in peribulbar block. ⋯ Considering the advanced age of most of these patients and the high concentrations of local anesthetics used in peribulbar blockade, the use of ropivacaine and levobupivacaine produces motor blockade as effective as racemic bupivacaine while minimising risks for cardiotoxicity.