Terapevt Arkh
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Comparative Study
[Adaptive and non-adaptive reactions of central hemodynamics to conditions of heat discomfort].
Chest rheography was used to study central hemodynamics in 134 healthy males aged 18-28 in comfortable weather conditions and discomfortable ones, that is at equivalent-effective temperature 17-24 degrees C and above 27-30 degrees C, respectively. In trained subjects from native and non-native population under comfortable weather conditions heart rate (HR) proved to be significantly reduced as compared to untrained subjects (57.6 +/- 1.1 and 56.2 +/- 1.2 against 73.9 +/- 1.7 and 70.4 +/- 0.9), whereas stroke volume in trained males was significantly larger (by 14.2 and 14.0%, respectively). Minute blood volume (MBV), cardiac and stroke indices, systolic and diastolic pressure showed no significant differences. ⋯ This was secured by stroke volume elevation by 14.3, 10.7 and 11.2%, respectively (p < 0.05), in non-natives by acceleration of heart rate by 11.2%. A trend to lowering of arterial pressure was more marked in untrained examinees of both populations. It is evident that in conditions of arid zone heat discomfort trained subjects from both native and non-native populations exhibited adequate hemodynamic responses, whereas strain was observed in circulatory system functioning when it adapted to heat discomfort in untrained non-natives.
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Twenty-three patients with Behçet's disease (BD) meeting the criteria of the international group for classification and diagnosis of BD (17 men and 6 women) were typed for HLA antigens class 1. The patients group was multinational, of them 19 were Caucasoids and 4 Mongoloids. It was shown that HLA B5 in Caucasoids occurred more frequently vs normal controls (73.7% and 15.5%, respectively). ⋯ In antigen group B5 + B35 the relative risk and association power grew still higher. The B5 positive group statistically more frequently had superficial thrombophlebitis and less frequently gastrointestinal involvement. It is concluded that class 1 HLA antigens, B5 in particular, are closely associated with BD in CIS countries.
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Multicenter Study Comparative Study
[The regional characteristics of the blood plasma lipid levels and of the indices of arterial pressure and physical development in schoolchildren of Russian nationality living in different climatic-geographic areas (based on the data from a single study in Ashgabad, Moscow, Orenburg, Tyumen and Tallinn)].
Random samples from a schoolchildren population living in different climatic and geographic regions were entered in the standard epidemiological survey. They were examined for plasma lipids vs. arterial pressure and physical development. Region-specific predictors of atherosclerosis were elucidated in Russian schoolchildren as an example. Cholesterol levels proved significantly higher in Tallinn schoolchildren (northwest territories), while the lowest ones occurred in Ashkhabad children (south territories).
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Comparative Study
[The morphofunctional properties of the blood cells and iron metabolism in the native inhabitants of the Taimyr Autonomous Okrug].
The peripheral blood was studied in Dolgans, Nganasans and Nenetses, the native population living in Taimyr peninsula. The composition of their blood is really different from the European norm. In Aboriginals of Taimyr the activity of erythropoietin in blood plasma, the concentration of reticulocytes, the circulation in peripheral bed of diskocytes with one and many diverticula, the content of fetal hemoglobin are raised more than two times. The prevalence of iron deficiency anemia among the native population of Taimyr Autonomous Area is larger, than in Russia and in Aboriginals living in Evenkia and Yakutia.
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A representative sample of native Selkup population (161 males and 237 females) aged 20-69 from the Tyumen region of the Russian Federation was examined for blood lipids using standard techniques. Measurement of mean cholesterol in males and females showed it to be 181.2 +/- 9.4 mg/dl and 188.2 +/- 8.5 mg/dl, respectively, that of low-density lipoproteins, high-density lipoproteins made up 112.0 +/- 9.7 mg/dl and 50.3 +/- 3.9 mg/dl for males and 118.4 +/- 9.0 mg/dl, 51.7 +/- 3.4 mg/dl, for females, respectively. ⋯ Overall atherogenic index averaged 2.9 +/- 0.3. The findings evidence that northern Selkups (both males and females) have much lower content of blood cholesterol and low-density lipoprotein cholesterol than control populations from Novosibirsk and Moscow.