Turk J Med Sci
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Randomized Controlled Trial
Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery.
To compare the postoperative analgesic efficacy and side effects of paracetamol and tramadol in patients undergoing lumbar disc surgery. ⋯ Paracetamol alone was not able to provide effective analgesia. Tramadol was more effective in the treatment of postoperative pain after lumbar disc surgery.
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Randomized Controlled Trial Comparative Study
Comparison of local infiltration anesthesia and peripheral nerve block: a randomized prospective study in hand lacerations.
To compare local infiltration anesthesia (LIA) and peripheral nerve block (PNB) in repairing hand lacerations. ⋯ Despite the fact that performing PNB in emergency departments requires some experience, it still counts as a convenient method comparable to LIA.
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To compare the changes in pain-related symptoms of inguinal hernias from initial admission to postoperative month 6 following 2 herniorrhaphy techniques. ⋯ Despite its ease of application and short time duration, self-gripping polypropylene mesh repair was not found to be superior to conventional Lichtenstein hernia repair in terms of reducing pain related to inguinal hernia.
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Human alveolar epithelial cells play a critical role in the pathogenesis of lung diseases. The objective of this study is to determine the contribution of beraprost sodium, a prostaglandin I2 (PGI2) analogue, to inflammatory and oxidative events in response to lipopolysaccharide (LPS) in airway epithelial cells. ⋯ These findings suggest that beraprost sodium will provide a pivotal molecular basis for the design of new therapeutic strategies to cure endotoxin-induced lung injury, although additional comprehensive studies are still required.
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Sepsis is still a major cause of morbidity and mortality despite the improvements in diagnosis and treatment. The aim of this study was to investigate the values of procalcitonin and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in the differential diagnosis of patients with sepsis and noninfectious systemic inflammatory response syndrome (NI-SIRS) and measure their importance in the prognosis of patients with sepsis. ⋯ In the differentiation of sepsis and NI-SIRS, and evaluation of the prognosis of sepsis, combined measurements of procalcitonin and sTREM-1 levels are important.