Turk J Med Sci
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Randomized Controlled Trial
Efficacy of wound infiltration with lornoxicam for postoperative analgesia following thyroidectomy: a prospective, randomized, double-blind study.
Postoperative pain control constitutes a major problem and studies have focused on reducing opioid requirements using regional techniques. We aimed to investigate the efficacy of wound infiltration with lornoxicam on postoperative pain control following thyroidectomy. ⋯ Wound infiltration with lornoxicam neither improved postoperative pain control nor decreased total analgesic consumption.
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Randomized Controlled Trial
The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection.
To compare the effects of tramadol-only treatment and tramadol + gabapentin treatment in patients who had received an epidural steroid injection. ⋯ This study revealed that tramadol + gabapentin treatment was not superior to tramadol treatment.
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Clinical manifestations of sepsis are not caused directly by the invading pathogens, but rather mostly by systemic inflammation that leads to activation of the coagulation system. The aim of this study was to determine whether levels of hemostasis- related parameters measured in intensive care unit admissions are associated with mortality and severity in patients with sepsis. ⋯ Hemostasis-related parameters have a significant impact on severity and outcome in sepsis.
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Sepsis is still a major cause of morbidity and mortality despite the improvements in diagnosis and treatment. The aim of this study was to investigate the values of procalcitonin and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in the differential diagnosis of patients with sepsis and noninfectious systemic inflammatory response syndrome (NI-SIRS) and measure their importance in the prognosis of patients with sepsis. ⋯ In the differentiation of sepsis and NI-SIRS, and evaluation of the prognosis of sepsis, combined measurements of procalcitonin and sTREM-1 levels are important.
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Randomized Controlled Trial
The effectiveness of ultrasound treatment for the management of knee osteoarthritis: a randomized, placebo-controlled, double-blind study.
A randomized, placebo-controlled, double-blind study was designed to investigate the effectiveness of ultrasound therapy in primary knee osteoarthritis. ⋯ Significant improvements in terms of pain, function, and quality of life scales were noted in both ultrasound groups in comparison with the placebo group. No statistically significant difference was found in terms of efficacy between the continuous and pulsed ultrasound.