Turk J Med Sci
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The evolution of sickle cell disease (SCD) is marked by the occurrence of painful episodes linked to the obstruction of microvessels by sickle cells, known as vaso-occlusive crisis (VOC). The aim of this work was to report the practical aspects of the management of acute pain in adults with SCD. Recommendations based on these practices are also provided. ⋯ Wide variability was observed in the modalities of analgesic treatment of sickle cell VOC. These variations reflect different views on the appropriateness of opioids. This study highlights the efficacy of multimodal analgesia in the management of acute pain in patients with SCD, particularly in regard to morphine sparing. Context-specific recommendations will be needed to harmonize practices.
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The heart, as the main part of the circulatory system, is one of the organs frequently affected by hematological diseases. Cardiac problems may develop during the course and treatment of benign and malignant hematological diseases. ⋯ Determining appropriate cardiac approaches in cases of hematological diseases with relevant knowledge and experience regarding the development of cardiac involvement in pathophysiological conditions has an important role in the diagnosis and treatment processes of patients. This review provides relevant information about hematological diseases and the heart, and key points that will help in the diagnosis and treatment process are presented.
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Review
Minimally invasive sacroiliac fusion: current insights and a comprehensive literature review.
The sacroiliac joint (SIJ) is a frequently overlooked source of lower back pain (LBP). Recently, it has gained recognition as a significant pain generator, prompting increased interest in surgeries targeting this area. Traditionally, open SIJ fusion was used to stabilize pelvic and sacral fractures, and then it was adapted for use in pain management until the development of minimally invasive surgery (MIS). Revolutionizing the field, MIS offers fast and effective pain relief with significantly less risk of postsurgical adverse events, thereby gaining increased attention among surgeons. This review aims to highlight the current advancements in the literature regarding MIS SIJ fusion. ⋯ The current literature demonstrates the superiority of MIS over open surgery with satisfactory patient outcomes and significantly lower complication rates. With the advancement in navigation and the inclusion of robotic assistance, MIS SIJ fusion is expected to become more ergonomically feasible for surgeons and shorten the learning curve for new trainees worldwide.
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The thyroid gland is one of the major regulator organs of hemostasis in the human body, controlling the functioning of numerous systems. Thyroid hormones exert a modulating effect on the cardiovascular system in particular, ensuring optimal functioning within the normal range. Triiodothyronine (T3), as an active form of thyroid hormone, is mainly responsible for this effect via both genomic and nongenomic mechanisms. ⋯ The pattern of cardiovascular abnormalities in subclinical thyroid disorders appears to parallel that of overt hypothyroidism, suggesting that even mild alterations in thyroid hormone levels may also have effects on the cardiovascular system. The management of subclinical thyroid disease remains controversial. Current evidence suggests that patient age and underlying cardiovascular diseases are major factors in clinical decision-making.
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The aim of this study is to examine the risks associated with the use of artificial intelligence (AI) in medicine and to offer policy suggestions to reduce these risks and optimize the benefits of AI technology. AI is a multifaceted technology. If harnessed effectively, it has the capacity to significantly impact the future of humanity in the field of health, as well as in several other areas. ⋯ These include increasing AI literacy, implementing a participatory society-in-the-loop management strategy, and creating ongoing education and auditing systems. Integrating ethical principles and cultural values into the design of AI systems can help reduce healthcare disparities and improve patient care. Implementing these recommendations will ensure the efficient and equitable use of AI systems in medicine, improve the quality of healthcare services, and ensure patient safety.