Vojnosanit Pregl
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Randomized Controlled Trial Comparative Study
The effects of different anesthesia techniques on free radical production after tourniquet-induced ischemia-reperfusion injury at children's age.
Reperfusion of previously ischemic tissue leads to injuries mediated by reactive oxygen species. The aim of the study was to investigate the effects of different anesthesia techniques on oxidative stress caused by tourniquet-induced ischemia-reperfusion (IR) injury during extremity operations at children's age. ⋯ Continuous propofol infusion and regional anesthesia techniques attenuate lipid peroxidation and IR injury connected with tourniquet application in pediatric extremity surgery.