Neurology
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Randomized Controlled Trial Multicenter Study Clinical Trial
Intranasal sumatriptan in cluster headache: randomized placebo-controlled double-blind study.
Current evidence-based acute treatments of cluster headache are limited to oxygen inhalation and subcutaneous sumatriptan. Intranasal sumatriptan is a new formulation with better tolerability than the subcutaneous route. Two open-label studies suggested efficacy of intranasal sumatriptan in cluster headache. ⋯ Sumatriptan nasal spray is effective and well tolerated in the acute treatment of cluster headache attacks of at least 45 minutes' duration.