Neurology
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Randomized Controlled Trial Multicenter Study Clinical Trial
Unilateral pallidotomy versus bilateral subthalamic nucleus stimulation in PD: a randomized trial.
To compare the efficacy of unilateral pallidotomy and bilateral subthalamic nucleus (STN) stimulation in patients with advanced Parkinson disease (PD) in a randomized, observer-blind, multicenter trial. ⋯ Bilateral STN stimulation is more effective than unilateral pallidotomy in reducing parkinsonian symptoms in patients with advanced PD.