Neurology
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Randomized Controlled Trial Multicenter Study Comparative Study
Efficacy of cabergoline in restless legs syndrome: a placebo-controlled study with polysomnography (CATOR).
To assess the efficacy and safety of the dopamine agonist cabergoline in the treatment of patients with idiopathic restless legs syndrome (CATOR study). ⋯ Single-evening cabergoline is an efficacious and well-tolerated short-term therapy for sensorimotor symptoms of restless legs syndrome and associated sleep disturbances.
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Randomized Controlled Trial Comparative Study Clinical Trial
High-frequency chest wall oscillation in ALS: an exploratory randomized, controlled trial.
To evaluate changes in respiratory function in patients with ALS after using high-frequency chest wall oscillation (HFCWO). ⋯ High-frequency chest wall oscillation was well tolerated, considered helpful by a majority of patients, and decreased symptoms of breathlessness. In patients with impaired breathing, high-frequency chest wall oscillation decreased fatigue and showed a trend toward slowing the decline of forced vital capacity.