Neurology
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Randomized Controlled Trial
Memantine induces reversible neurologic impairment in patients with MS.
Cognitive dysfunction is very common in multiple sclerosis (MS) and it severely impairs patients' quality of life. Thus, we explored whether memantine might improve cognitive performance in patients with MS. ⋯ Memantine at a dose of 30 mg/day may induce transient worsening of neurologic symptoms of multiple sclerosis.