Neurology
-
Randomized Controlled Trial Multicenter Study Comparative Study
Sun exposure and vitamin D are independent risk factors for CNS demyelination.
To examine whether past and recent sun exposure and vitamin D status (serum 25-hydroxyvitamin D [25(OH)D] levels) are associated with risk of first demyelinating events (FDEs) and to evaluate the contribution of these factors to the latitudinal gradient in FDE incidence in Australia. ⋯ Sun exposure and vitamin D status may have independent roles in the risk of CNS demyelination. Both will need to be evaluated in clinical trials for multiple sclerosis prevention.
-
Multicenter Study Comparative Study
Metabolic syndrome and cognitive decline in French elders: the Three-City Study.
To examine associations between metabolic syndrome (MetS) and its individual components with risk of cognitive decline on specific cognitive functions. ⋯ MetS as a whole and several of its components had a negative impact on global cognitive decline and specific cognitive functions in older persons.