Neurology
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Multicenter Study Observational Study
Thrombolytic therapy for stroke in patients with preexisting cognitive impairment.
We aimed to evaluate the influence of prestroke cognitive impairment (PSCI) on outcomes in stroke patients treated with IV recombinant tissue plasminogen activator (rtPA). ⋯ This study provides Class IV evidence that in patients with PSCI presenting with acute ischemic stroke, IV rtPA improves outcomes.