Neurology
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Randomized Controlled Trial
Mind-body therapy via videoconferencing in patients with neurofibromatosis: An RCT.
To test, within a single-blind randomized controlled trial, the feasibility, acceptability, efficacy, and durability of a mind-body program (the Relaxation Response Resiliency Program for neurofibromatosis [3RP-NF]) vs an attention placebo control (Health Enhancement Program for NF [HEP-NF]), both delivered via group videoconferencing. ⋯ This study provides Class II evidence that for patients with NF, a mind-body program is superior to an attention placebo control in improving QoL.
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Randomized Controlled Trial Multicenter Study
Chronic migraine headache prevention with noninvasive vagus nerve stimulation: The EVENT study.
To evaluate the feasibility, safety, and tolerability of noninvasive vagus nerve stimulation (nVNS) for the prevention of chronic migraine (CM) attacks. ⋯ This study provides Class II evidence that for patients with CM, nVNS is safe, is well-tolerated, and did not significantly change the number of headache days. This pilot study lacked the precision to exclude important safety issues or benefits of nVNS.