Clin Nephrol
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Meta Analysis
Tenecteplase for the improvement of blood flow rate in dysfunctional hemodialysis catheters.
We evaluated the efficacy and safety of the thrombolytic agent tenecteplase for the treatment of dysfunctional hemodialysis (HD) catheters. ⋯ Tenecteplase, administered as a 1-h dwell or a 1-h dwell followed by an extended dwell, was associated with improved BFR in dysfunctional HD catheters in the TROPICS 3 and 4 clinical trials.