Obstetrics and gynecology
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Obstetrics and gynecology · May 1999
Randomized Controlled Trial Comparative Study Clinical TrialTopical lidocaine-prilocaine versus lidocaine for neonatal circumcision: a randomized controlled trial.
To evaluate epicutaneous application of 5% lidocaine-prilocaine and 30% lidocaine cream anesthetics for neonatal circumcision. ⋯ Epicutaneous 5% lidocaine-prilocaine was more effective than 30% lidocaine for neonatal circumcision, better reducing neonatal stress indicators. Lidocaine-prilocaine significantly shortened crying time during one of the most painful phases of circumcision. Both topical anesthetics were more effective than placebo in attenuating the behavioral and physiologic indicators of neonatal pain.