Obstetrics and gynecology
-
Obstetrics and gynecology · Mar 2019
Multicenter Study Comparative StudyOral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas: A Randomized Controlled Trial.
To investigate the noninferiority of relugolix compared with leuprorelin acetate in reducing heavy menstrual bleeding associated with uterine leiomyomas. ⋯ Takeda Pharmaceutical Company Limited and an affiliate of NovaQuest Capital Management LLC.
-
Obstetrics and gynecology · Mar 2019
Meta Analysis Comparative StudyLetrozole Compared With Clomiphene Citrate for Unexplained Infertility: A Systematic Review and Meta-analysis.
To estimate the clinical effectiveness, as determined by positive pregnancy test, of letrozole compared with clomiphene citrate for ovarian stimulation in patients with unexplained infertility. ⋯ Although limited by heterogeneity, studies of ovarian stimulation in women with unexplained infertility show no difference in clinical outcomes between letrozole and clomiphene citrate.