Obstetrics and gynecology
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Obstetrics and gynecology · Mar 2019
Multicenter Study Comparative StudyOral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas: A Randomized Controlled Trial.
To investigate the noninferiority of relugolix compared with leuprorelin acetate in reducing heavy menstrual bleeding associated with uterine leiomyomas. ⋯ Takeda Pharmaceutical Company Limited and an affiliate of NovaQuest Capital Management LLC.
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Obstetrics and gynecology · Mar 2019
Randomized Controlled Trial Comparative StudyPessary Compared With Vaginal Progesterone for the Prevention of Preterm Birth in Women With Twin Pregnancies and Cervical Length Less Than 38 mm: A Randomized Controlled Trial.
To compare the effectiveness of cervical pessary to vaginal progesterone for the prevention of preterm birth in women with twin pregnancies and short cervix. ⋯ ClinicalTrials.gov, NCT02623881.
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Obstetrics and gynecology · Mar 2019
Meta Analysis17α-Hydroxyprogesterone Caproate and the Risk of Glucose Intolerance in Pregnancy: A Systematic Review and Meta-analysis.
To evaluate whether 17α-hydroxyprogesterone caproate use in preventing preterm birth increases the risk of gestational diabetes mellitus (GDM). ⋯ PROSPERO, CRD42016041694.
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Obstetrics and gynecology · Feb 2019
Comparative StudyPostoperative Opioid Consumption After Scheduled Compared With Unscheduled Cesarean Delivery.
To identify characteristics associated with high inpatient daily opioid consumption after cesarean delivery. ⋯ For a quarter of women undergoing cesarean delivery, daily consumption of opioids is equivalent to 10 tablets of oxycodone 5 mg daily. No characteristics were associated with high opioid use for women having a scheduled or unscheduled cesarean delivery. Understanding opioid consumption after cesarean delivery is critical to managing women's postoperative pain while decreasing opioid exposure and risks of long-term opioid use disorder.
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Obstetrics and gynecology · Jan 2019
Randomized Controlled TrialEffects of Two Educational Posters on Contraceptive Knowledge and Intentions: A Randomized Controlled Trial.
To compare the Centers for Disease Control and Prevention's (CDC) contraceptive effectiveness poster with a more patient-centered poster on factors affecting the likelihood of using effective contraceptives. ⋯ ClinicalTrials.gov, NCT03372369.