Obstetrics and gynecology
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Obstetrics and gynecology · May 2011
Multicenter StudyAdmixture mapping to identify spontaneous preterm birth susceptibility loci in African Americans.
Preterm birth is 1.5 times more common in African American (17.8%) than European American women (11.5%), even after controlling for confounding variables. We hypothesize that genetic factors may account for this disparity and can be identified by admixture mapping. ⋯ Spontaneous preterm birth in African American women may be genetically mediated by a susceptibility locus on chromosome 7. This region contains multiple potential candidate genes, including collagen type 1-α-2 gene and genes involved with calcium regulation.
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Obstetrics and gynecology · Jan 2011
Multicenter StudyPostpartum hemorrhage resulting from uterine atony after vaginal delivery: factors associated with severity.
To identify factors associated with severity of postpartum hemorrhage among characteristics of women and their delivery, the components of initial postpartum hemorrhage management, and the organizational characteristics of maternity units. ⋯ II.
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Obstetrics and gynecology · Dec 2010
Multicenter StudyContemporary patterns of spontaneous labor with normal neonatal outcomes.
To use contemporary labor data to examine the labor patterns in a large, modern obstetric population in the United States. ⋯ In a large, contemporary population, the rate of cervical dilation accelerated after 6 cm, and progress from 4 cm to 6 cm was far slower than previously described. Allowing labor to continue for a longer period before 6 cm of cervical dilation may reduce the rate of intrapartum and subsequent repeat cesarean deliveries in the United States.
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Obstetrics and gynecology · Oct 2010
Randomized Controlled Trial Multicenter StudyTranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial.
To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding. ⋯ I.
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Obstetrics and gynecology · Jun 2010
Multicenter Study Comparative StudyComparison of transverse and vertical skin incision for emergency cesarean delivery.
To compare incision-to-delivery intervals and related maternal and neonatal outcomes by skin incision in primary and repeat emergent cesarean deliveries. ⋯ II.