Anesthesia, essays and researches
-
Alpha-2 adrenergic agonists clonidine and dexmedetomidine, are well known to produce analgesia through an opioid independent mechanism. Alpha-2 agonists are used as an adjuvant to local anesthetic agents to extend the duration of spinal, epidural and brachial plexus blocks. ⋯ The addition of dexmedetomidine to low dose ropivacaine for CEA could shorten the onset of sensory block and extend the duration of analgesia with optimum sedation without episodes of hypoxemia as compared to addition of clonidine to ropivacaine.
-
Clonidine added to bupivacaine prolongs the duration of anesthesia and postoperative analgesia with minimal side effects. Ropivacaine has lower lipid solubility and better safety profile as compared to bupivacaine. This study is designed to evaluate the effects of low-dose clonidine when added to hyperbaric ropivacaine. ⋯ Addition of low-dose clonidine to intrathecal hyperbaric ropivacaine causes a significant prolongation of the duration of sensory and motor blockade as well as postoperative analgesia compared with saline placebo. However, it increases the incidence of hypotension and bradycardia which can be managed with routine clinical measures.
-
Unanticipated difficult intubation can be challenging to anesthesiologists, and various bedside tests have been tried to predict difficult intubation. ⋯ The diagnostic accuracy of NC/TM ratio and Mallampatti score were better compared to other bedside tests to predict difficult intubation in Indian population.
-
Anesthetic management of pheochromocytoma is complicated and challenging. Extra-adrenal pheochromocytoma is a rare neuroendocrine tumor that produces, stores and secretes catecholamines. The main-stay in the management of pheochromocytoma surgeries is Preoperative preparation which has improved perioperative outcome. ⋯ Resection of the tumor results in acute withdrawal of catecholamines, which may lead to severe hypotension. In perioperative period, adequate hydration should be maintained. Beta-blockers, nitroglycerine, sodium nitroprusside and phenylephrine are required to avoid hemodynamic fluctuations and should be used appropriately.
-
Propofol has been used for the induction and maintenance of anesthesia. However, patients experience vascular pain during its injection. ⋯ The results indicate an effect of the lipid type on delayed pain reduction, especially propofol-MCT/LCT. On the other hand, the lidocaine decreases immediate propofol-LCT vascular pain.