BMC anesthesiology
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Meta Analysis
The effect of intravenous lidocaine on postoperative cognitive dysfunction: a systematic review and meta-analysis.
Postoperative cognitive dysfunction (POCD) has been reported as a significant complication in elderly patients. Various methods have been proposed for reducing the incidence and severity of POCD. Intravenous lidocaine administration has been reported in the literature to reduce POCD, but the effect of lidocaine remains controversial. ⋯ Lidocaine administered intravenously could attenuate the overall incidence of POCD and its severity in the short term.