BMJ open
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Review Comparative Study
Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale.
To provide a comprehensive comparison of patent foramen ovale (PFO) closure versus medical therapy in patients with cryptogenic stroke or transient ischaemic attack (TIA) and demonstrated PFO. ⋯ Pooled data from three RCTs provides insufficient support that PFO closure is preferable to medical therapy for secondary prevention of cryptogenic stroke in patients with PFO.
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Review Comparative Study
Systematic review of percutaneous closure versus medical therapy in patients with cryptogenic stroke and patent foramen ovale.
To provide a comprehensive comparison of patent foramen ovale (PFO) closure versus medical therapy in patients with cryptogenic stroke or transient ischaemic attack (TIA) and demonstrated PFO. ⋯ Pooled data from three RCTs provides insufficient support that PFO closure is preferable to medical therapy for secondary prevention of cryptogenic stroke in patients with PFO.