Anaesthesiologie und Reanimation
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Measurement of heart rate variability (HRV) in the perioperative period is not yet part of routine monitoring. Because of a lack of standardization, comparison of results of different investigations is difficult. Caution is needed in interpreting data of HRV measurements because of the complexity of autonomic control of the cardiovascular system. ⋯ Because of the ongoing progress in monitoring with regard to acquisition and computer-based analysis of HRV data, it seems at least possible to measure HRV routinely in the perioperative setting. However, the need for standardization requires large prospective and standardized trials. Depending on the results, the clinical relevance of HRV as a relatively simple and non-invasive perioperative monitoring has to be re-evaluated.
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Anaesthesiol Reanim · Jan 2001
Review Comparative Study[Clinical administration of muscle relaxants for intubation].
Muscle relaxants are used for tracheal intubation, surgical procedures and in the intensive care unit. This review describes muscle relaxants available in Germany, with special focus on their use in endotracheal intubation. We compare the advantages and disadvantages of succinylcholine (the only depolarising agent) with those of short- and intermediate-acting non-depolarising agents in an attempt to define the characteristics of the ideal muscle relaxant. ⋯ The advantages and disadvantages of using non-depolarising instead of depolarising agents are discussed using data from our studies and those of other research groups. Possible side-effects due to the chemical structure and the necessary dosage for intubation of different agents are also discussed. Two points are emphasized: firstly, the use of non-depolarising agents for intubation requires the possibility of safe ventilation of the patient via mask, and, secondly, it is important that procedures be performed by an experienced anaesthetist.